Safe and sustained pain relief with a single injection
A novel treatment for adults with knee osteoarthritis
Osteoarthritis in the knee
Osteoarthritis (OA) of the knee is the most common form of arthritis and its incidence is rising. Without a cure, the most effective treatment remains total knee arthroplasty.
A growing demand for new non-surgical treatments
There has been little successful innovation in treating OA over the past 20 years, and apart from surgery, there are few treatment options that can offer long-term benefits to patients.
Potential therapeutic advances have been made, targeting pathways of cartilage catabolism and anabolism, as well as regenerative strategies based on stem cells but more research is needed before these treatments become widely available.
AN INTRA-ARTICULAR POLYACRYLAMIDE HYDROGEL (iPAAG) A NOVEL THERAPEUTIC CONCEPT
Arthrosamid® is an intra-articular polyacrylamide hydrogel injection (iPAAG). It is a non-biodegradable single-dose injection that delivers long-acting and sustained pain relief, improving the quality of life for patients with knee osteoarthritis.
WHAT IS iPAAG?
Intra-articular polyacrylamide hydrogel injection (iPAAG) in Arthrosamid® is made of 2.5% cross-linked polyacrylamide and 97.5% water.
Biocompatible: permeable to salts and organic molecules the hydrogel is able to integrate with soft tissue
Viscoelastic: cross-linked chains of polymer allow flexible shear
Non-degradable: structural stability of hydrogel provides longevity of action
20 YearsOf research and development
SafeFor intended use
700,000Hydrogel injections have been given
A familiar technique
Arthrosamid® treatment is a minimally invasive out-patient procedure. It should be performed under local anaesthesia, with ultrasound guidance.
It is essential that at least 5 cm around the injection site is swabbed prior to the injection. Local anaesthetic is used to numb the injection site. The same needle is set in place for the whole procedure.
Remove joint effusion, if present, before injecting Arthrosamid®. The injection should be performed with the help of ultrasound in the lateral proximal recess.
Remove the protective tip cap from the Arthrosamid® syringe and inject the hydrogel. This is repeated until 6ml of Arthrosamid® is delivered.
Remove the needle and place a plaster over the Arthrosamid® injection site. You can immediately weight bear on the treated limb.
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