Safe and sustained pain relief with a single injection

A new class of injectable therapy to treat for adults with knee osteoarthritis.

Osteoarthritis in the knee

Knee Osteoarthritis (OA) is the most common form of arthritis, and its incidence is rising. Without a cure, the most effective treatment remains total knee arthroplasty.

A growing demand for new non-surgical treatments

There has been little successful innovation in treating osteoarthritis (OA) over the past 20 years, and apart from surgery, there are few treatment options that can offer long-term benefits to patients.

Potential therapeutic advances have been made, targeting pathways of cartilage catabolism and anabolism, as well as regenerative strategies based on stem cells but more research is needed before these treatments become widely available.

“However, surgery is not right for every patient, leaving many people in continued discomfort."
IPAAG Orange

INTRODUCING Arthrosamid logo


Arthrosamid® is an injectable polyacrylamide hydrogel (iPAAG) for intra-articular administration. It is a non-biodegradable single-dose injection that delivers long-acting and sustained pain relief, improving the quality of life for patients with knee osteoarthritis.

Arthrosamid Box Orange


Intra-articular polyacrylamide hydrogel injection (iPAAG) in Arthrosamid® is made of 2.5% cross-linked polyacrylamide and 97.5% water.

Biocompatible: permeable to salts and organic molecules the hydrogel is able to integrate with soft tissue

Viscoelastic: cross-linked chains of polymer allow flexible shear

Non-degradable: structural stability of hydrogel provides longevity of action

iPAAG: injectable polyacrylamide hydrogel


Permeable to salts and organic molecules the hydrogel is able to integrate with soft tissue


Cross-linked chains of polymer allow flexible shear


Structural stability of hydrogel provides longevity of action

Undergone over

20 Years

Of research and development


For intended use


Hydrogel injections have been given

A familiar technique

Arthrosamid® treatment for knee osteoarthritis that is a minimally invasive out-patient procedure. It should be performed under local anaesthesia, with ultrasound guidance.

Technique 1
It is essential that at least 5 cm around the injection site is swabbed prior to the injection. Local anaesthetic is used to numb the injection site. The same needle is set in place for the whole procedure.
Technique 2
Remove joint effusion, if present, before injecting Arthrosamid®. The injection should be performed with the help of ultrasound in the lateral proximal recess.
Technique 3
Remove the protective tip cap from the Arthrosamid® syringe and inject the hydrogel. This is repeated until 6ml of Arthrosamid® is delivered.
Technique 4
Remove the needle and place a plaster over the Arthrosamid® injection site. You can immediately weight bear on the treated limb.

Want to use Arthrosamid®?

Safe and sustained pain relief with a single injection. Clinicians who would like to learn to use Arthrosamid® for their knee osteoarthritis patients can get in touch with us for further details.

Want to see our results?

Arthrosamid® provides safe and sustained pain relief with a single injection.

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