Arthrosamid® remains safe and effective[21,23] for its intended use 5 years after treatment.[41]

CLINICAL STUDIES	Retrospective Case Series* (mean FU: 2 years)[22]	IDA Study (up to 5 years)[7,21]	ROSA Study (up to 3 years)[7,23]
No. of participants	91	49	121
Related AEs, subjects, n(%)	25 (27%)	12 (24.5%)	35 (28.9%)
Related AEs, events, n	41	14	41
Most frequent
Pain from target knee	7	6	21
Joint Swelling	-	4	13
Sensation of distension	15	-	-
Reduced range of motion	4	-	-
Synovial Cyst	-	3	-
Other	15	1	7

^{*Of note, retrospective case series uses adverse events, not adverse device effects}

No intra-articular infections or allergic reactions were reported in this retrospective study[22]