Our Solution

Introducing Arthrosamid®

Long-lasting, proven pain relief for knee OA — without surgery

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What is Arthrosamid®?

  • Based on an innovative non-biodegradable hydrogel technology, Arthrosamid® is 2.5% cross-linked polyacrylamide and 97.5% water.


  • The medical description of Arthrosamid® is an 'injectable polyacrylamide hydrogel' otherwise known as '2.5 iPAAG'. 
  • Approved for treatment of knee OA, Arthrosamid® is suitable, safe and effective for most patients with the condition.


  • Arthrosamid® is the first and only approved injectable treatment that permanently combines with the knee’s synovial tissue — decreasing joint stiffness, diminishing pain, improving the function of the knee, and enhancing your quality of life.
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Arthrosamid® is a permanent injectable hydrogel that delivers long-lasting, proven pain relief without surgery — redefining treatment for knee OA.

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Supported by more than two decades of research, Arthrosamid® is proven to be safe and effective — offering you long-lasting pain relief for your knee OA.

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Arthrosamid® is proven to maintain a significant, long-lasting reduction in knee OA pain  — even three years post-treatment.

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Without surgery

Arthrosamid® is a simple, one-step procedure performed under local anaesthesia by a qualified physician — without surgery.

How does Arthrosamid® (iPAAG) work?

  • Arthrosamid® combines with the tissue lining your knee joint,thickening it to provide a barrier — reducing your pain.


  • Arthrosamid® permanently combines with the tissue lining your knee joint and it’s this unique characteristic that provides a significant reduction in your OA pain over a longer period — with one single treatment.
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Why choose Arthrosamid®?

No therapies have been able to satisfactorily halt or delay OA progression or provide effective, long-lasting symptomatic relief for patients with knee OA. So, until now, treatments have tended to focus on pain relief and the management of symptoms through:

  •  Weight loss
  • Exercise and physiotherapy
  • Walking aids
  • Footwear and insoles
  • Knee braces
  •  Oral pain relief medication
  • Viscosupplement Hyaluronic Acid (HA) injections

and when these therapies fail

  •  Joint replacement/ knee surgery.
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What are the benefits?

Unlike hyaluronic acid injectables — where there is very little evidence to show that the effect is still noticeable at six months 

  •  Arthrosamid® provides a significant reduction in your knee OA pain over a longer period with one single treatment.


Treatment with Arthrosamid® is a simple, one-step outpatient procedure 

  • Performed in a day that doesn’t involve the disruptive recovery period usually associated with surgery. 

Ready to take the next step?

If your pain has not been improved by over-the-counter painkillers or lifestyle changes to diet and exercise, it may be time to talk to your doctor about Arthrosamid®.

It is important to bear in mind that there is no cure for osteoarthritis but successful treatment with Arthrosamid® may reduce or relieve your knee pain. You should also bear in mind that your knee osteoarthritis may not improve and, in some cases, may get worse.

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