Hit back at Knee Osteoarthritis

Arthrosamid® is a new type of treatment that offers patients an effective alternative to currently available therapies.1 It is a non-biodegradable hydrogel (iPAAG) that is injected into the knee to cushion the joint and relieve pain.



Arthrosamid® is injected into the intra-articular space as a minimally invasive, out-patient procedure. You do not need to stay in hospital for treatment and clinicians are very familiar with injections into the knee joint.


Arthrosamid® is safe for intended use and is biocompatible which allows it to integrate with the tissues in your knee. The overall safety profile of the hydrogel has undergone two decades over of research and development with approximately 1,000,000 hydrogel units used for various indications in the body.


In clinical trials, patients reported a reduction in their pain levels by Week 4 after their injection. The reduction in pain was sustained over 156 weeks. Arthrosamid® trials will continue to follow patients for 5 years.

What is Knee Osteoarthritis?

Knee osteoarthritis (arthritis that affects the knee bones/joints) is a long-term condition that worsens over time, causing pain and disability. It is most common in the knee joint, where it wears away the shock-absorbing cartilage and causes the bones to rub together. As a result the joint becomes stiff, swollen and painful.

No one knows exactly what causes knee osteoarthritis. There is no permanent cure and, until now, treatments have focused on managing the symptoms. They include:

  • Exercise
  • Weight Loss
  • Pain Relief Medication
  • Viscosupplement Injections
  • Braces
  • Physio

When these therapies fail total knee replacement surgery is often the only option. Things are about to change.

Technique 4

What is Arthrosamid®?

Arthrosamid® is a new type of treatment for knee osteoarthritis that offers patients an effective alternative to the currently available therapies. Based on an innovative non-biodegradable hydrogel technology, Arthrosamid® is 2.5% cross-linked polyacrylamide and 97.5% water. When injected into the knee Arthrosamid® cushions the joint and reduces pain, providing safe and sustained relief, all with one injection.

Technique 3

How does it work?

Arthrosamid® is an intra-articular polyacrylamide hydrogel injection (iPAAG) for the symptomatic treatment of knee osteoarthritis. Once injected into the inner joint cavity, it restores viscosity within the synovial fluid, improving lubrication and cushioning of the joint. Arthrosamid® also integrates into the synovium of the inner joint capsule creating a cushion-like effect.

Technique 2

The Benefits of Arthrosamid®

Because Arthrosamid® works to cushion the joint, it can reduce your pain, decrease stiffness, and help movement. It has been shown to be safe and can give long-acting pain relief, improving your quality of life.